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Ketoconazole liver toxicity
Ketoconazole is an antifungal medication which is used primarily to treat fungal infections. … In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially in those that are benign such as hirsutism.Because of its potential for severe adverse reactions including hepatotoxicity, ketoconazole has been withdrawn in many countries and has strict labeling in the…Biomed Environ Sci. 2013 Jul;26(7):605-10. doi: 10.3967/0895-3988.2013.07.013. Ketoconazole associated hepatotoxicity: a systematic review and meta-…19 Sep 2014 … While cases of potential ketoconazole-associated hepatoxicity were reported as early as 1984 (three years after the drug received FDA…18 Jan 2017 … However, histopathological changes revealed that fluconazole was the most hepatotoxic, followed by ketoconazole, itraconazole, terbinafine,…19 Jun 2013 … June 19, 2013. Subject: KETOCONAZOLE and the Risk of potentially Fatal Liver Toxicity. Dear Health Care Professional,. The manufacturers of…Ketoconazole has only recently been recognized as a cause of hepatic injury, ….. other known hepatotoxic drugs or other causes of hepatic and outcome of the…injury was uncommon with fluconazole (2.0 [1.4-2.7]), ketoconazole (2.9 [1.1-6.3]), and … One patient developed acute liver failure due to ketoconazole.17 Nov 2015 … One patient developed acute liver failure due to ketoconazole. Pre-existing chronic liver disease increased risks of aminotransferases >200 U/L…15 Sep 2017 … Ketoconazole may cause liver damage, sometimes serious enough to require liver transplantation or to cause death. Liver damage may occur…
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