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In general, most patients who experienced adverse reactions during the topamax first eight weeks of these trials no longer experienced them by their last visit . Table 6 topamax lists the incidence of adverse reactions that occurred in at least 1% of adults treated with 200 to 400 mg/day TOPAMAX� (and also higher daily dosing of 600 mg to 1000 mg) in controlled trials and that was numerically greater with TOPAMAX� than with placebo . Table 9 lists the incidence of treatment-emergent adverse reactions that occurred in at least 1% of pediatric patients treated with 5 to 9 mg/kg TOPAMAX� in controlled trials and that was numerically greater than the incidence topamax in patients treated with placebo .
aPatients in topamax these add-on/adjunctive trials were receiving 1 to 2 concomitant antiepileptic drugs in addition to TOPAMAX� or placebo .

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